1843-45: Rev. Thomas F. Mulledy, S.J.
1845-48: Rev. James Ryder, S.J.
1848-51: Rev. John Early, S.J.
1851-54: Rev. Anthony F. Ciampi, S.J.
1854-57: Rev. Peter J. Blenkinsop, S.J.
1857-61: Rev. Anthony F. Ciampi, S.J.
1861-67: Rev. James Clark, S.J.
1867-69: Rev. Robert W. Brady, S.J.
1869-73: Rev. Anthony F. Ciampi, S.J.
1873-78: Rev. Joseph B. O'Hagan, S.J.
1878-83: Rev. Edward D. Boone, S.J.
1883-87: Rev. Robert W. Brady, S.J.
1887-89: Rev. Samuel Cahill, S.J.
1889-93: Rev. Michael O'Kane, S.J.
1893-95: Rev. Edward A. McGurk, S.J.
1895-1901: Rev. John F. Lehy, S.J.
1901-06: Rev. Joseph F. Hanselman, S.J.
1906-11: Rev. Thomas E. Murphy, S.J.
1911-18: Rev. Joseph N. Dinand, S.J.
1918-24: Rev. James J. Carlin, S.J.
1924-27: Rev. Joseph N. Dinand, S.J.
1927-33: Rev. John M. Fox, S.J.
1933-39: Rev. Francis J. Dolan, S.J.
1939-45: Rev. Joseph R. N. Maxwell, S.J.
1945-48: Rev. William J. Healy, S.J.
1948-54: Rev. John A. O'Brien, S.J.
1954-60: Rev. William A. Donaghy, S.J.
1960-70: Rev. Raymond J. Swords, S.J.
1970-94: Rev. John E. Brooks, S.J.
1994-98: Rev. Gerard Reedy, S.J.
1998-2000: Frank Vellaccio, Ph.D. (Acting President)
2000-2012: Rev. Michael C. McFarland, S.J.
2012- 2021: Rev. Philip L. Boroughs, S.J.
2021-present - Vincent D. Rougeau