
Danielle Metterville explains her work to Prof. Mary Lee Ledbetter and senior Derek Palacio.
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The 24th Annual
Biology Undergraduate
Research Symposium
Callahan Science Library Atrium
May 4, 2005
20 students presented their research. Of these, 18 were graduating senior biology majors (out of a class of 48). Their work ranged from community ecology to molecular biology (press here for a listing of all of the titles and faculty sponsors).
Four biology majors received awards from the Biology or Chemistry Departments or the College.
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Paul Lavoie , '05, (above) with his poster. Paul's work in Dr. Mary Lee Ledbetter's lab dealt with the ability of cells to communicate chemically via gap junctions. On graduation, Paul plans to get a research job while he decides between medical and graduate school. |

Kate Freeman '05 and her research advisor, Prof. George Hoffmann. Kate will be attending the University of Pennsylvania medical school next year where she is considering also earning a PhD. Kate did a year and a half of research on genetic rearrangements that occur in cells after exposure to agents that induce mutations. She was also a member of the College Honors program and a dedicated (and powerful) varsity rower. |
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Senior Marisa Carbonaro worked with Prof. Kornath Madhavan on a developmental biology problem that dealt with the role of a chemical signal on pattern formation in flies, Marisa is headed to graduate school in pharmacology at Cornell University Medical School in New York City.
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Ecology student extraordinaire Bridget Collins, '05, (below) explains here work on stream ecology to Dr. Robert Bertin. Bridget will begin graduate school in ecology at the University of Delaware where she has a fellowship. Bridget's research advisor was Prof. William Sobczak.

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The tall dude with the big smile is Christian Levenick, hometown Pasadena CA. Here, he explains his project to Dr. Mary Bruno and Cathy Dumas. Christian is graduating senior who worked with Prof. William Sobczak on the effects of the loss of eastern hemlock trees to an invasive insect, the hemlock wooly adelgid, on the rate of decomposition in small streams. Christian plans to attend veterinary school.
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Lindsey Bomar, '05, (below) explains her work to Profs. Robert Bertin (l) and William Sobczak. Lindsey's work dealt with water quality issues in local streams and grew out of projects she did in her microbiology and aquatic ecology courses. She continued the work her last semester without seeking formal credit! Lindsey was also a varsity track star. She plans to work for a year or two before attending graduate school. Lindsey was advised by Profs. Madeline Vargas and William Sobczak.

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Megan Doe (above) worked for both semesters of her senior year (and the summer preceding) at UMASS Medical School's Department of Molecular Biology and Microbiology with at Drs. David Mangus and Allan Jacobson, Megan's project that involved using molecular biological techniques to help solve protein interactions. Megan will begin graduate school in molecular biology next fall at Dartmouth. Her Holy Cross advisor was Prof. Cara Constance.
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Meredith Irwin (above) presents a posted based on her College Honors thesis. Meredith's was a field work project dealing with differences in forest composition as a influenced by previous land use in a state park just northwest of Worcester. Her advisor was Prof. Robert Bertin. Meredith spent her junior year in Dijon France. In the short term Meredith hopes to work with government agency such as the EPA and then she plans to attend graduate school, probably in some area associated with environmental policy. |

Senior Matt Ronan (above) explains his work on mutagenesis to another student. Matt is eventually headed to medical school but has decided to do research for a year or two in a university/medical center lab in order to help him to decide if he also wants to pursue a research degree. Matt's research advisor was Prof. George Hoffmann.
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Katherine Lewandowski (below) will enter graduate school in molecular biology at Washington University in St. Louis in the fall. Here, she presents her work, done with Dr. Kenneth Mills of the Chemistry Department on the mechanism by which a protein is modified after its initial synthesis. Katie was also a member of the biochemistry concentration.

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Erika Babineau (above) studied the molecular basis of biological clocks with Prof. Cara Constance. She plans to attend graduate school but for the next year or two she will work as a research assistant at a large university. |
The scene during the poster session 
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Danielle Metterville(above) will work in a research lab for a year or two before attending graduate school in some area of molecular biology. In addition to being an accomplished science student, Danielle is an accomplished actor and has appeared in several of the theatre department's productions. Danielle's work was part of a larger project dealing with the function of potassium channels in biological clocks. Danielle's research advisor was Prof. Cara Constance.
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Sheila Lynch, '05, below, did her work on the effects of a drug that inhibits ion movements on the expression of proteins that are found in gap junctions. Her research sponsor was Dr. Mary Lee Ledbetter. Besides her research and studies, Sheila was a residence hall advisor. This fall Sheila will begin her graduate studies in science education at St. Joseph's University where she has received a fellowship.

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Dan Sammartino's research was in Prof. Mary Lee Ledbetter's lab. Dan worked on chemical communication through gap junctions. Dan will do research for a year before attending medical school.
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Senior Jon Rainey did his field work at Olympic National Park in Washington where he studied the daily vertical migrations of plankton. He plans to work for a year or two before attending graduate school. His advisor was Prof. William Sobczak.

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Bellin Lab Personnel. Seniors Luke Duncan (Chemistry) and Hillary Barnes (Biology) with Professor Rob Bellin (center). Both Hillary and Luke are members of the Biochemistry Concentration, a program that allows students to delve into more depth in biochemistry by taking relevant courses in both departments and then doing a year of research.
Hillary worked to develop a means to detect the activation of a process involved in generating cellular responses to the mechanical stresses that act on cells. She will attend the University of Maryland Medical School in the fall.
Luke's work also involved the mechanism by which cells respond to mechanical forces. He worked out a means to assure that mechanical forces would be applied to one particular group of transmembrane proteins (syndecans) that are suspected as being involved in transmitting strain from the outside to the inside a cell.
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Sophomore Brian Matthews (below) presents his work with Prof. Karen Ober. Brian obtained samples of mitochondrial and nuclear DNA that were sequenced and used to answer question in beetle systematics. Brian is also co-chair of the Biology Society.

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Seniors Laura McGregor and Katie Debit studied the rates that Giardia infects beavers and muskrats that live in the Paunchiest Reservoir (part of Boston's water supply). Next year, Laura will teach high school but then plans to head to medical school. Katie will also work for a year, hopefully with the EPA and then she plans to attend graduate school, probably in some aspect of environmental policy. Katie and Laura worked with Prof. William Sobczak.
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Professor Cara Constance (center) and research students Danielle Metterville (l) and Erika Babineau (r).

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Kate Freeman, '05, Professor Emeritus Peter Parsons (biochemistry) and Professor George Hoffmann.

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Erika Babineau
Analysis of Circadian Clock Gene Expression in Xenopus tropicalis
Dr. Cara Constance, faculty sponsor
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Hillary Barnes Development of a MAP Kinase Assay to Study Syndecan-Based Mechanotransduction
Dr. Robert Bellin, faculty sponsor
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Lindsey Bomar A Comparative Study of Coliform Densities in Worcester’Äôs Urban Blackstone River and Forested Headwaters
Drs. Madeline Vargas and William Sobczak, faculty sponsors
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Marisa Carbonaro The Role of Retinoic Acid in the Sternal Pattern Formation of Musca domestica
Dr. Kornath Madhavan, faculty sponsor
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Bridget M. Collins Subsurface Flowpaths Drive Spatial Variation in the Macroinvertebrate Community of an Intermittent Headwater Stream in Central New England
Dr. William Sobczak, faculty sponsor
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Katherine B. Dietz and Laura E. McGregor Evaluating the Presence of Giardia lamblia in the Quabbin and Wachusett Reservoirs’Äô Beaver and Muskrat Populations
Dr. William Sobczak and Dr. Robert Bellin, faculty sponsors
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Megan R. Doe Identification of Single Amino Acid Changes in Pab1p that Eliminate Interaction with Sup35p
Drs. David Mangus and Allan Jacobson, UMASS Medical School and Dr. Cara Constance, faculty sponsors.
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Deirdre M. Dorval A Study of the RIR Inteins in Pyrococcus abyssi
Dr. Kenneth Mills, Department of Chemistry, faculty sponsor
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Luke Duncan (chemistry major) Surface Modification of Polydimethylsiloxane for the Study of Mechanotransduction
Dr. Robert Bellin, faculty sponsor
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Kate Freeman Coincident Genetic Events in Yeast
Dr. George Hoffmann, faculty sponsor
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Meredith Irwin
Forest Composition and Land-Use History at Moore State Park, Paxton, Massachusetts
Dr. Robert Bertin, faculty sponsor
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Paul Lavoie Expression of Connexin 43 in Communication-Competent Cells and Its Induction by Transfection in Cells Unable to Communicate
Dr. Mary Lee Ledbetter, faculty sponsor
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Christian E. Levenick Changes in Leaf Decomposition Rates and Macroinvertebrate Communities within Streams Draining Eastern Hemlock Forests: Indirect Impacts of the Hemlock Woolly Adelgid Invasion
Dr. William Sobczak, faculty sponsor
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Katherine Lewandowski Post-Translational Modifications Catalyzed by HINT Domains
Dr. Kenneth Mills, Department of Chemistry, faculty sponsor
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Sheila Lynch
Does Ouabain Affect Expression of Connexin43 in 293T/17 Cells? Experiments with Western Blots
Dr. Mary Lee Ledbetter, faculty sponsor
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Brian Matthews Molecular Systematics of the Beetle Tribe Lachnophorini and Related Harpalines: Bald is Beautiful
Dr. Karen Ober, faculty sponsor
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Danielle Metterville Establishing Transgenic Xenopus tropicalis and a Behavioral Assay to Investigate the Role of Potassium Channels in the Circadian Clock
Dr. Cara Constance, faculty sponsor
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Jonathan D. Rainey Diel Distribution of Zooplankton in Lake Crescent, Olympic National Park
Dr. William Sobczak, faculty sponsor
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Matthew Ronan Interaction between Bleomycin and Intercalating Agents in the Induction of Gene Conversion and Mutations in Saccharomyces cerevisia
Dr. George Hoffmann, faculty sponsor
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Daniel Sammartino The Effects of Ouabain on the Communication through Gap Junctions of the 293T/17 and 293T Cell Lines
Dr. Mary Lee Ledbetter, faculty sponsor |
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