General Biology 2 -- Class Materials and Schedule
(Biology 121)

Spring Semester 2008

College of the Holy Cross

Dr. Ken Prestwich

Thursday -- Note, there were two (-) signs missing from the answer key to the problem set entitled "Excitable Cell Physiology – Resting Potentials" -- the answer to #1 should be - 99.83mV and the Em for #2 should be - 99.53mV. Sorry about the mistakes.

The final review session will be on Friday (tomorrow) at 9 AM in our classroom.

I will send an email either on Thursday of Friday as to the composition of the final exam.

CLASS SCHEDULE

Part 1. The Phenotype: Genetic expression and development.

Jan. 16 (W)
Cl #1


Introduction. Review of regulation. Unfinished business -- the regulation of genetic expression in prokaryotes.

Handouts and Assignments

Also be certain that you have read over the class information sheet and have looked over this webpage.

Review of negative feedback control and an intuitive model of regulation of opened systems.

Jan. 18 (F)
Cl #2

Gene regulation, continued. An introduction to the regulation of gene expression in eukaryotes.

Handouts and Assignments
Jan. 21 (M)
No Classes -- The Reverend Martin Luther King Jr. Day

Jan. 23 (W)
Cl #3

Development & multicellularity.

Handouts and Assignments
Jan. 25 (F)
Cl #4

Development continued.
Handouts and Assignments

Part 2. Animals and Energy - emphasis on movement and digestion.

Jan. 28 (M)
Cl #5

Finish development.

Handouts and Assignments

text readings -- same as previous class

Jan. 30 (W)
Cl #6

Metabolism and temperature regulation.

Handouts and Assignments

Feb. 1 (F)
Cl #7

Temperature regulation.
Handouts and Assignments

Feb. 4 (M)
Cl #8

Finish temperature regulation.
Muscle morphology, histology and EC-coupling.
Handouts and Assignments

Feb. 6 (W)
Cl #9

Excitation contraction coupling in skeletal muscles. The effect of muscle fiber length on muscle force.
Handouts and Assignments

text readings -- same as previous class

Feb. 8 (F)
Cl #10

Mechanical function – Elasticity.

Handouts and Assignments
same as previous class

Feb. 11 (M)
Cl #11

Muscle fiber types and recruitment.
A brief consideration of the skeleton
Material for exam #1 ends with contraction. .
-- i.e., the exam does NOT include digestion

Skeletal micro structure and role in Ca++ metabolism. (NOT ON EXAM)

Handouts and Assignments
Part 3. The Digestive, circulatory and respiratory systems.

Feb. 13 (W)
Cl #12

Skeletal Levers
Begin digestion.

Handouts and Assignments
SAME SKELETON NOTES AS ABOVE
Feb. 15 (F)
Cl #13
EXAM #1 -- all material through the digestive system.
Feb. 18 (M)
Cl #14

More to digest.

Handouts and Assignments
Feb. 20 (W)
Cl #15

Finish digestion -- chemical digestion and hormonal coordination of digestion.

Handouts and Assignments
Feb. 22 (F)
Cl #16

THE CIRCULATION
Overview.
The operation of the heart.

Handouts and Assignments

Circulation handout #1
(same as the one previously listed with 2/20 class)

Feb. 25 (M)
Cl #17

Operation of the heart continued. Electrical and mechanical function of the heart.
Brief overview of electrocardiograms.

Handouts and Assignments
Feb. 27 (W)
Cl #18

Brief overview of the ECG and its uses, continued.
The vascular system.

Handouts and Assignments
Feb. 29 (F)
Cl #19

The vascular system and the regulation of the circulation.
Handouts and Assignments

March 1 - 9

Spring Break

March 10 (M)
Cl #20

Blood vessels and the regulation of the circulation by the autonomic ns and metabolites.
Hydraulic filtering, blood flow and blood pressure
.

Handouts and Assignments

same as previous class

March 12 (W)
Cl #21

Finish the vascular system -- review of blood pressure.
Lymph
Blood cells
END MATERIAL FOR EXAM #2
Handouts and Assignments

March 14 (F)
Cl #22

Oxygen transport.
Handouts and Assignments

Blood gas transport handout. (originally given with class #21)

Resource -- Wikipedia article on Hb -- especially look over the animations lower on the page.

March 17 (M)
Cl #23

March 19 (W)
Cl #24

EXAM #2

EASTER BREAK -- March 20 (Thru) through 24 (MON)

March 26 (W)
Cl #25

Carbon dioxide transport.
The lungs and their morphology. Elasticity and breathing.
Airways, resistance, and breathing.

Handouts and Assignments
Please read Campbell, pp 884-890
This is a simple but worthwhile overview, the notes at left are more complete. There are no questions for this section as they are covered in the handout notes.
March 28 (F)
Cl #26

Finish breathing.

Handouts and Assignments
March 31 (M)
Cl #27

Finish breathing.
Acid - base.
Handouts and Assignments

Part 4. Excretion and water balance.
April 2 (W)
Cl #28

Acid-base.
Excretion overview.

The morphology and general function of mammalian kidneys.

Handouts and Assignments
April 4 (F)
Cl #29

The structure and operation of the kidney.
Clearance.

Handouts and Assignments

same reading as class #29

April 7 (M)
Cl #30


Finish clearance.
Water conservation and the hormonal control of kidney function

Handouts and Assignments
Part 5: Immunity.

April 9 (W)
Cl #31

Hormonal control of the kidney, continued.
Begin the Immune system.

Handouts and Assignments

Class #31 PP notes -- CHC access only

April 11 (F)
Cl #32

Finish innate immunity -- END MATERIAL FOR EXAM #3 WITH INNATE IMMUNITY
Begin acquired immunity

Handouts and Assignments

Campbell, Ch. 43 -- Immunity
Questions and text term list

April 14 (M)
Cl #33

Finish immune system

Handouts and Assignments

April 16 (W)
Cl #34

EXAM #3 -- material through innate immunity

April 18 (F)
Cl #35

Finish immunity

Handouts and Assignments
Part 6. The Nervous and sensory systems.
April 21 (M)
Cl #36

overview of nervous system
resting potentials

Handouts and Assignments
April 23 (W)
Cl #37

"Moving" potentials -- electrotonic and action potentials.
Neural integration and cellular networks.

Handouts and Assignments

Same as above

April 25 (F)
Cl #38

"Moving" potentials -- electrotonic and action potentials.
Neural integration and cellular networks.

Handouts and Assignments
Part 8. Populations and evolution.

April 28 (M)
Cl #39

Finiah neural computation (use remainder of Friday's PP notes).
The genetics of populations – microevolution and the H-W equilibrium

Handouts and Assignments

April 30 (W)

STUDY PERIOD BEGINS

May 3 (SAT.)
 Comprehensive Final Exam 2:30 PM

College of the Holy Cross

The Biology Department

Ken Prestwich's Homepage

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